Priligy is a medication belonging to the selective serotonin reuptake inhibitor devoted to premature ejaculation treatment.
History of Creation
The unexpected effect of the drug was discovered by accident, which unites it with famous Viagra. Pharmacologists of the world known «Johnson & Johnson»the company had a clear mission: to create a universal antidepressant, which regulates the circulation of the so-called «hormone of happiness» – serotonin – in the brain. Thus Priligy was born.
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Clinical trials were conducted with the participation of men aged from 18 to 60 years. It was observed that the drug eliminates depression because of its impact not only on neurotransmitters but also on sexual intercourse duration. The participants in the study, as well as clinicians themselves, were surprised to find such a pleasant property of the drug. It completely eliminates the problem of premature ejaculation, while multiplying pleasure from orgasm.
Of course, high efficiency and safety of this drug for the body should also be noted. Dapoxetine is rapidly absorbed by body and excreted during a few hours – it is its main difference from antidepressants, which removal process can take several days.
This PE drug has passed clinical trials in more than 22 countries around the world, in which it proved to be highly effective. It is able to delay orgasm and prolong sex by 3 – 4 times. It’s really overwhelming figures.
Also, it should be noted that dapoxetine is very well combined with pills for erectile dysfunction treatment – with Viagra, Levitra, Cialis, regardless of their dosage. Efficacy of the latter does not decrease.
Priligy active ingredient – dapoxetine, which increases serotonin level (natural chemical substance) that can slow process of ejaculation. It can also increase a sense of control over the ejaculation process and time. In the process of this medication application, increased time to ejaculation leads to increased feelings of control over ejaculation.
Mechanism of Action
It is assumed that dapoxetine action at premature ejaculation is associated with serotonin reuptake inhibition by neurons followed by neurotransmitter action amplification in pre- and post-synaptic receptors.
Ejaculation mechanism is mainly regulated by the sympathetic nervous system. Postganglionic sympathetic nerve fibers innervate seminal vesicles, deferent canal, prostate, urethra and muscles of the bladder neck, causing the coordinated contraction to achieve ejaculation. Dapoxetine affects ejaculation reflex, increasing latent period and reducing the duration of reflex impulses of perineum ganglia motoneurons. Stimulus triggering ejaculation is generated in a spinal reflex center which via brain stem is controlled by several brain nuclei including paraventricular and preoptic.
How to Use Priligy?
The main indication for Priligy is premature ejaculation. In addition, it well helps in daily therapy and has a significant impact on the emotional state of a person. If you have problems with sex, you suffer from premature ejaculation, this drug is for you. It will help to solve this problem and forget about it.
It should be taken properly and always according to instructions or advice of experts. Like any medicine, there are side effects and contraindications. It is categorically contraindicated to take the drug without a prescription. Only a doctor can prescribe this drug after medical examination and testing.
Causes of premature ejaculation can be different – you need to decide first whether you really need serotonin inhibitors. Of course, dosage regimen is also determined by a specialist. Based on conducted experiments, the drug gives an immediate and long-lasting effect. Instruction for use prohibits taking more than one pill per day. It is also necessary then to consider that effect of the drug appears after 30 – 60 minutes. Priligy can be used regardless of food.
It is necessary to exclude alcohol while taking the drug because alcoholic beverages can lower efficiency of medicine or cause unwanted adverse reactions. Its effect lasts for three to four hours. During therapy, patients are recommended to regularly visit the doctor, who will closely monitor changes in the body.
Modern medicine recommends taking the drug with caution to men who have suffered from mental alienation. Conditional contraindications include kidney diseases, coagulation disorders, epilepsy – in such cases, additional researches are needed.
Always follow rules of admission, follow instructions and do not break advice from your physician. This may have an opposite effect. And you, instead of enjoying life and sexual contact, will be hospitalized.
Posted by Dr. Himanshu Singh