Buy Cheap Daklinza (Daclatasvir) Online

In the battle against hepatitis C, accessibility to effective and affordable treatment options is crucial for individuals worldwide. Hepatitis C is a viral infection that affects the liver, leading to progressive damage if left untreated. Fortunately, medical advancements have revolutionized hepatitis C treatment, and one such breakthrough medication is Daklinza (Daclatasvir).

Daklinza, a direct-acting antiviral (DAA), has shown exceptional efficacy in combating the hepatitis C virus (HCV). It is widely prescribed as part of combination therapy to suppress viral replication and achieve sustained virologic response (SVR), indicating a cure for hepatitis C. However, the high cost of brand-name Daklinza 60 mg has created barriers to access for many patients in need.

To address this challenge, the availability of generic Daklinza (Daclatasvir) 60 mg offers a more affordable alternative without compromising its effectiveness. The emergence of online pharmacies has further simplified the process of obtaining generic medications, making it easier for individuals to access the treatment they require.

What is Daklinza (Daclatasvir)?

Daklinza (Daclatasvir) is a prescription medication that is primarily used for the treatment of chronic hepatitis C, a viral infection that affects the liver. It belongs to a class of medications called direct-acting antivirals (DAAs) and works by targeting the hepatitis C virus (HCV) to inhibit its replication and spread in the body.

The drug is often prescribed as part of a combination therapy, which means it is used alongside other antiviral medications. The specific combination of medications and treatment duration may vary depending on factors such as the HCV genotype, liver condition, and individual patient characteristics.

The active ingredient in this drug, Daclatasvir, targets a specific protein called NS5A, which is essential for the replication of the hepatitis C virus. By blocking the NS5A protein, Daklinza helps prevent the virus from multiplying, reducing its presence in the body.

The effectiveness of the medicine has been demonstrated across various HCV genotypes, including genotype 1, 2, 3, and 4. Treatment with this medicine aims to achieve sustained virologic response (SVR), which indicates the successful eradication of the hepatitis C virus and a potential cure.

It is important to note that these pills should only be used under the supervision and prescription of a healthcare professional who specializes in hepatitis C treatment. They will assess the patient’s condition, conduct relevant tests, and determine the most suitable treatment plan, including the dosage and duration of daclatasvir.

How it works

Daklinza (Daclatasvir) is a direct-acting antiviral (DAA) medication that specifically targets the hepatitis C virus (HCV) and disrupts its replication process within the body.

Daclatasvir 60 mg primarily acts by inhibiting a viral protein called NS5A, which is crucial for the replication and assembly of the hepatitis C virus. By blocking NS5A, the substance interferes with the virus’s ability to form new copies of itself, thereby reducing the viral load in the body.

In addition to inhibiting NS5A, daclatasvir also contributes to the restoration of normal liver function. Chronic hepatitis C infection can lead to inflammation and damage to liver cells. Daklinza helps to improve liver health by reducing the viral load and allowing the liver to heal and regenerate.

This medicine is often prescribed in combination with other antiviral medications, such as sofosbuvir or ribavirin, to enhance treatment efficacy. The combination therapy works synergistically to attack the virus from different angles, further inhibiting its replication and increasing the chances of achieving a sustained virologic response (SVR), which indicates a cure for hepatitis C.

Indications for use

This medicine is used in combination with other antiviral drugs as part of a comprehensive treatment approach. The indications for Daklinza use include:

  1. HCV Genotypes: The drug is effective against different genotypes of the hepatitis C virus, including genotype 1, 2, 3, and 4. It is prescribed based on the specific genotype of the HCV infection.
  2. Treatment-Naive Patients: The drug is indicated for individuals who have not previously received treatment for chronic hepatitis C. It can be used as an initial therapy to combat the infection.
  3. Treatment-Experienced Patients: It is also prescribed for patients who have previously received treatment for chronic hepatitis C but did not achieve a sustained virologic response (SVR) with their prior therapy. Daklinza offers an alternative treatment option for these individuals.
  4. Compensated Cirrhosis: Daclatasvir can be used in patients with compensated cirrhosis, a stage of liver disease where the liver is damaged but still functions adequately. It provides a treatment option for individuals with both chronic hepatitis C and compensated cirrhosis.
  5. HIV Coinfection: Daclatasvir can be used in patients coinfected with both chronic hepatitis C and HIV. However, appropriate consideration of drug interactions and dosage adjustments is necessary in such cases.


Here’s a table outlining the recommended dosage information for Daklinza (Daclatasvir):

Recommended DosageThe recommended dosage of Daklinza is 60 mg taken orally once daily. It is usually administered in combination with other antiviral medications as part of a comprehensive treatment regimen for chronic hepatitis C. The specific combination therapy, duration of treatment, and dosage adjustments may vary based on factors such as HCV genotype, liver condition, and individual patient characteristics.
AdministrationDaclatasvir tablets should be taken by mouth with or without food. They should be swallowed whole with a sufficient amount of water and should not be crushed, chewed, or broken before ingestion.
Timing of AdministrationThe medicine can be taken at any time of the day, preferably around the same time each day, to maintain a consistent dosing schedule.
Missed DoseIf a dose of Daclatasvir is missed and it is within 12 hours of the usual dosing time, the missed dose should be taken as soon as possible. If it is more than 12 hours, the missed dose should be skipped, and the next dose should be taken at the regular scheduled time. Doubling the dose to make up for a missed one should be avoided.
Special Populations and Considerations– Renal Impairment: No dosage adjustment is necessary for patients with mild to moderate renal impairment. However, the medicine should be used with caution in patients with severe renal impairment or end-stage renal disease, as limited data is available.<br>- Age, Gender, and Body Weight: No dosage adjustment is required based on age, gender, or body weight considerations.
Coadministration with HIVWhen Daclatasvir is coadministered with certain HIV antiretroviral medications, dosage adjustments may be necessary due to potential drug interactions. Healthcare professionals will carefully evaluate the concomitant medications and determine the appropriate dosage modifications, if required.

Instructions for use

Using Daklinza (daclatasvir) in the treatment of Hepatitis C requires specific instructions. Here are the general steps for using it, but remember these guidelines should not replace your doctor’s advice. Always adhere to your healthcare provider’s instructions and consult with them if you have any queries or uncertainties.

  • Dosage and Timing: The drug is usually prescribed as a 60 mg dose, to be taken orally once per day. However, your healthcare provider may modify this depending on your medical status, treatment response, among other considerations.
  • When to Take: The tablet can be consumed with or without meals. To ensure a steady level of the medication in your system, try to take it at a consistent time each day.
  • How to Take: The tablet should not be crushed, chewed, or broken apart. It needs to be swallowed whole.
  • In Case of a Missed Dose: If you forget to take a dose of Daclatasvir 60 mg, take it as soon as you recall. But, if it’s close to the time for your next dose, omit the missed dose and proceed with your normal schedule. Don’t double up doses to compensate for a missed one.
  • Concurrent Medications: Daclatasvir is typically prescribed in combination with other antiviral drugs for the treatment of Hepatitis C. Ensure you take all medicines as directed by your healthcare provider.
  • Duration of Treatment: Your treatment period may differ based on your health condition, but it generally ranges from 12 to 24 weeks. It’s crucial to complete the full course of Daklinza 60 mg tablet as prescribed, even if you feel better before the treatment period is over.

Side effects

Here are some of the common and more severe side effects you might experience with Daklinza 60 mg.

1. Common Side Effects: These are typically less severe and occur more frequently. They include:

  • Feelings of fatigue or exhaustion
  • Occasional headaches
  • Feelings of nausea
  • Sleep disturbances or insomnia

These effects are generally temporary and may disappear as your body adjusts to the medicine. If they persist or worsen, it is crucial to reach out to your healthcare provider.

2. Severe Side Effects: These occur less frequently but are more critical. Immediate medical attention is necessary if you experience any of the following symptoms:

  • Intense pain in the stomach or abdomen
  • Urine of a dark color
  • Yellowing of the skin or eyes (jaundice)
  • Persistent feelings of nausea or episodes of vomiting
  • Symptoms of a severe infection (such as a consistent fever, persistent sore throat)
  • Signs of liver disease (such as persistent vomiting, nausea, abdominal pain, yellowing skin or eyes, dark urine)

Please note that this is not an exhaustive list of all possible side effects of Daklinza. If you experience any other concerning symptoms, it’s crucial to consult with your healthcare provider immediately.

While this medicine can have side effects, its benefits in treating Hepatitis C generally outweigh the potential risks. Regular visits to your healthcare provider are important to monitor your body’s response to the treatment and to swiftly identify and manage any side effects. Always seek professional medical advice from your healthcare provider.

Contraindications for use

Here’s a table of potential contraindications for Daklinza (daclatasvir):

HypersensitivityPatients with known hypersensitivity to daclatasvir or any other component in this medicine. This could include symptoms such as rash, itching, swelling, severe dizziness, and trouble breathing.
Severe liver impairmentAlthough Daklinza is a treatment for hepatitis C, a liver disease, it may not be suitable for patients with severe liver impairment. The effect of this drug on these patients might be unpredicted and could potentially worsen their condition.
Co-administration with certain drugsDrugs like rifampin, St. John’s wort, carbamazepine, phenytoin, phenobarbital, and others can significantly decrease the concentration of Daclatasvir in the blood, leading to reduced therapeutic effect and development of resistance.
Co-administration with strong inhibitors of CYP3A4When the drug is taken with strong inhibitors of the enzyme CYP3A4, it can increase the concentration of Daclatasvir in the blood, which might increase the risk of adverse effects.
PregnancyIt’s unclear whether this medicine could harm an unborn baby, so it’s not generally recommended during pregnancy unless the potential benefits outweigh the potential risks.
BreastfeedingIt’s unknown whether Daclatasvir passes into breast milk, so caution is recommended for breastfeeding mothers.
HIV co-infection without appropriate antiretroviral therapyThe drug should not be used in patients with co-infection of HIV-1 without concomitant antiretroviral therapy due to the potential for HIV-1 viral rebound.
Patients with rare hereditary problemsRare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.

But it’s still important to note that contraindications can vary based on individual patient circumstances, and this is not a comprehensive list. All potential contraindications or concerns should be discussed with a healthcare provider before starting a new medication.

Precautions and warnings

  • Liver Disease: As Daklinza is processed in the liver, careful monitoring is necessary for patients with any degree of liver disease, since they are at a higher risk for experiencing harmful side effects. Thoughtful consideration is needed when using this medicine in patients with severe liver cirrhosis as there have been reports of liver failure and associated fatalities after its use.
  • Interactions with Other Medications: Daclatasvir 60 mg has the potential to interact with numerous other drugs, particularly those that are broken down by the CYP3A liver enzyme. Medications that either strongly boost or inhibit this enzyme can alter the levels of Daclatasvir in the body, which might compromise its effectiveness or enhance side effects.
  • Hepatitis B Virus Reactivation Risk: Instances of reactivation of hepatitis B virus (HBV) have been reported in patients co-infected with HBV and HCV who were undergoing or had completed treatment with HCV direct-acting antivirals without concurrent HBV antiviral therapy. This reactivation can trigger severe liver complications, including liver failure and death.
  • Pregnancy and Lactation: The potential impacts of this drug on a developing fetus are not fully known, and it is uncertain whether it can be transmitted through breast milk. Patients should be advised to inform their healthcare provider if they become pregnant during the treatment period. Breastfeeding mothers should discuss with their healthcare provider about whether to stop breastfeeding or discontinue the medication, considering the medication’s necessity for the mother.
  • HIV Co-Infection: For patients co-infected with HIV-1, Daklinza 60 mg should not be administered without simultaneous antiretroviral therapy due to the risk of HIV-1 virus rebound.
  • Patients with Uncommon Genetic Disorders: Individuals with rare inherited conditions, such as galactose intolerance, the Lapp lactase deficiency, or glucose-galactose malabsorption, should not take this medication.
  • Heart Rhythm Issues: It’s not advised to use this drug with sofosbuvir in patients taking amiodarone due to the risk of serious slow heart rate symptoms.

Interactions with other drugs

Daklinza (Daclatasvir) 60 mg can interact with other medications, potentially impacting its efficacy or increasing the likelihood of side effects. Some notable interactions are listed below:

  • CYP3A Metabolized Drugs: Daclatasvir is majorly processed by the CYP3A enzyme in the body. Other medications that stimulate or inhibit this enzyme can modify Daclatasvir’s blood levels. Strong inducers of CYP3A, such as rifampin or St. John’s wort, may reduce Daclatasvir’s concentration, potentially undermining its efficacy. On the other hand, strong inhibitors of CYP3A, like ketoconazole or ritonavir, may increase Daclatasvir’s concentration, potentially elevating the risk of side effects.
  • Amiodarone: If Daklinza is used in combination with sofosbuvir and amiodarone, a medication used for heart rhythm disorders, there could be a severe decrease in heart rate. This combination is usually avoided unless absolutely necessary and only with meticulous cardiac monitoring.
  • Antiretroviral Medications: For patients co-infected with HIV-1, it is suggested that Daclatasvir be used in conjunction with antiretroviral therapy. Not doing so could result in an increased risk of HIV-1 disease progression.
  • Antacids and H2 Antagonists: Co-administration of this drug with antacids or H2 antagonists can lessen the absorption of Daclatasvir, thereby reducing its efficacy. It’s typically recommended to administer Daklinza 60 mg tablet 4 hours before or 2 hours after these types of medications.
  • Direct-acting Antivirals: Daclatasvir is often co-administered with other direct-acting antivirals for treating hepatitis C, such as sofosbuvir. The interactions between these medications and their collective effect on liver health should be closely observed.

Please note, this list does not encompass all potential drug interactions. It’s always advisable to consult with a healthcare provider or pharmacist about possible drug interactions prior to initiating any new medication while on these pills. Make sure to provide them with a comprehensive list of all prescription and over-the-counter drugs, vitamins, and herbal supplements currently in use.


To preserve the effectiveness of Daklinza (daclatasvir), proper storage is essential.

The tablets should remain in their original container with the label intact until it’s time for their use. The optimal storage condition for Daclatasvir is at room temperature, ideally around 25°C (77°F). Brief fluctuations between 15°C and 30°C (59°F and 86°F) are generally acceptable.

The tablets should be kept in a place that is dry and not exposed to direct light, so you should avoid locations that are too humid or exposed to sunlight, such as bathrooms and areas near windows. Storing the medicine in the refrigerator or freezer is not recommended as very cold temperatures can have a negative impact on the medication.

To prevent accidental consumption, ensure that this drug is stored out of the reach and sight of children and pets.

It’s crucial to check the expiry date on the drug container before beginning your treatment. Do not use the medication past this date. For proper disposal of expired or unused tablets, get guidance from your pharmacist or a local waste disposal company.

For any queries or concerns about how to store your medications, always reach out to your healthcare provider or pharmacist.

Frequently Asked Questions

What should I do if I miss a dose of Daklinza 60 mg?

If you miss a dose, take it as soon as you remember unless it’s close to the time for your next dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double up to make up for a missed dose.

How should I store Daklinza 60 mg tablet?

The drug should be stored at room temperature, ideally around 25°C (77°F). It should be kept in a dry place, away from direct light, and out of reach of children and pets.

What are the contraindications for Daklinza?

The medicine is contraindicated in individuals with a known hypersensitivity to daclatasvir, and it should not be used with drugs that strongly induce CYP3A and P-gp as this could lead to lower exposure of daclatasvir and reduced therapeutic effect.

What precautions should I take while on Daklinza 60 mg?

Regular liver function tests should be conducted while on treatment. Additionally, heart rate should be monitored in patients co-administered with amiodarone. If you have a history of hepatitis B, it may reactivate during or after treatment with these tablets.

Does Daklinza cure Hepatitis C?

When used in combination with other antiviral medications, the drug can cure Hepatitis C in many cases. The goal of the treatment is to achieve a sustained virologic response, which is essentially a cure.

What is Daklinza price?

The brand-name drug tends to carry a hefty price tag, however, an equally effective alternative is available in the form of a generic version. The cost of generic daclatasvir is roughly $540 for a pack of 28 tablets.


Tim: “Effective, but not without side effects. Experienced fatigue and occasional headaches. However, my Hep C is now under control, so it’s a win.”

Mary: “I had very few side effects, and after the 12-week course, my Hepatitis C is now undetectable. The treatment was easier than I expected. Very grateful for Daklinza.”

Steven: “Daklinza 60 mg, along with my other meds, helped clear my Hep C. It’s been 6 months since I completed my treatment, and I’m still virus-free. Experienced some mild side effects, but nothing too serious.”

Linda: “I had a hard time with these pills. The side effects were too much for me to handle, and I had to discontinue the treatment.”

Peter: “The drug worked well for me. I completed a 24-week course, and I’m happy to say I’m now Hep C free! The side effects were minor, and I managed them with my doctor’s help.”

Monica: “I was on generic Daklinza and Sovaldi for 12 weeks. I did experience some side effects like fatigue and occasional headaches, but overall it was tolerable. I’m just glad I’m finally free of Hep C.”

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