Advair Diskus (Fluticasone/Salmeterol)

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Drug Category:


Advair Application:

Asthma, Chronic Obstructive Pulmonary Disease, COPD, Bronchitis, Emphysema, Breathing

Advair Generic names:

Fluticasone/Salmeterol, Seretide, Viani, Adoair, ForAir, advair diskus, Seroflo

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What is Canadian Pharmacy Advair?

Canadian Advair is a drug used as a means for bronchospasm relief.

Advair drug used to treat COPD diseases. The drug is recommended to patients that use inhaled glucocorticosteroids in their therapy, and those patients whom glucocorticosteroids do not bring symptoms relief.

It should be remembered that this drug requires a sufficiently long-term reception for diseases treatment, as well as preventive care. Do not discontinue Advair usage in case of temporary health state improvement and disease symptoms disappearance. Read a detailed description of what Canadian Pharmacy Advair is…

Generics of Canadian Pharmacy Advair

Canadian Pharmacy Advair consists of: salmeterol xinafoate – to eliminate symptoms – and fluticasone propionate – to improve respiratory function. Also: fluticasone prevent disease exacerbations. Lactose is used as powder inhaler filling material.

Pharmacy chains offer some medications that can replaced Advair in accordance with a physician approval: Berodual, Berodual H, Symbicort Turbuhaler, etc.

Drug price depends on seller and, of course, on drug dose.

Canadian Pharmacy Advair Dosage

This medicinal product is intended for inhalation. Dosage depends on patient’s condition severity and age.

  • Children aged 4 – 12 years are recommended two inhalations a day at the rate of 25 mcg of salmeterol and 50 mcg of fluticasone.
  • Adults and adolescents aged 12 years and older are recommended to use drug twice a day at the rate of 25 mcg of salmeterol and 50 mcg of fluticasone or 25 mcg of salmeterol and 125 mcg of fluticasone.
  • The third option of dosage – at the rate of 25 mcg of salmeterol and 250 mcg of fluticasone.

It is important to remember: at all dosage options inhalation must be carried out twice a day.


You need to know that at present moment there is no information on Canadian Advair overdose. There is information only about its components overdose.

Salmeterol overdose causes tremor and headaches, while fluticasone suppresses adrenal function. In the first case it is necessary to withdraw Advair drug, in the second – it is allowed to continue treatment with the drug. This is due to the fact that adrenal function independently recovered in a few days.

In pharmacies the drug is released only on physician prescription. More detailes about Advair dosage…

Side Effects

For this medication two kinds of possible adverse symptoms are characteristic, which are related to each of its components. Fluticasone may cause paradoxical bronchospasm, hoarseness, mouth or throat candidosis. Salmeterol can affect cardiovascular system – violate heart rate, cause headaches (of vascular origin). There possible allergic reactions on the substance such as angioneurotic shock or rash.

Patients, treated from COPD, can obtain pneumonia. In addition, Canadian Pharmacy Advair can cause:

  • sickness;
  • mouth and throat irritation;
  • abdominal pains;
  • vomiting;
  • taste disorders;
  • hypokalemia;
  • anxiety;
  • muscle spasms;
  • hyperglycemia;
  • arthralgia;
  • tremor;
  • in rare cases – sleep disorders, behavioral disorders, including irritability and hyperactivity – in most cases these symptoms are observed at children.


According to instruction Canadian Advair is contraindicated to children under 4 years old, patients who have allergy to drug components. Advair is prescribed with caution for:

  • respiratory tract infections of fungal, viral or bacterial origin;
  • diabetes;
  • uncontrolled arterial hypertension;
  • thyrotoxicosis;
  • pulmonary tuberculosis;
  • arrhythmia;
  • hypoxia;
  • ischemic heart disease;
  • hypertrophic subaortic stenosis;
  • hypothyroidism;
  • glaucoma;
  • cataract;
  • lactation period;
  • pregnancy… See a full list of Canadian Pharmacy Advair contraindications…


Because of bronchospasm risk it is recommended to avoid selective and non-selective beta-adrenergic blocking agent, except for cases where they are essential.

In normal situations fluticasone propionate inhalations are accompanied by its low concentrations in blood plasma due to intensive metabolism during «first pass» and high systemic clearance under cytochrome P450 CYP3A4 isoenzyme influence in intestinal tract and liver. Due to this clinically significant interactions involving fluticasone propionate are unlikely.

Drug interactions research has shown that ritonavir – a highly active CYP3A4 isoenzyme inhibitor – can cause a sharp increase in fluticasone propionate concentration in blood plasma, resulting in significantly reduced serum cortisol concentrations. During post-approval observations there were received reports of clinically significant drug interactions at patients receiving fluticasone propionate (intranasally or by inhalation) together with ritonavir. This interaction causes side effects such as Cushing’s syndrome and adrenal function suppression. Given this, it is recommended to avoid simultaneous use of fluticasone propionate and ritonavir, unless potential benefit to patient outweighs risk of glucocorticosteroids systemic side effects.

Studies have shown that other CYP3A4 inhibitors produce negligible (erythromycin) and minor (ketoconazole) increased fluticasone propionate content in blood plasma, with almost no decrease in serum cortisol concentrations. Despite this, it is advisable to be careful while applying fluticasone propionate and potent CYP3A4 inhibitors (e. g., ketoconazole), since such combinations do not exclude probability of increased fluticasone propionate concentration in blood plasma, which could potentially increase systemic fluticasone propionate effects.

When studying drug interactions it was found that ketoconazole use as concomitant systemic therapy salmeterol concentration in blood plasma significantly increases. This can lead to QTc interval lengthening. Caution must be performed at combined use of potent CYP3A4 inhibitors (e. g., ketoconazole) and salmeterol.

Xanthine derivatives, glucocorticosteroids and diuretics increase hypokalemia risk (especially at patients with acute bronchial asthma exacerbations, during hypoxia).
MAO inhibitors and tricyclic antidepressants increase side effects risk for cardiovascular system.

Advair Canadian Pharmacy is compatible with cromoglicic acid.

Advair Canadian Pharmacy and Alcohol

Doctors always insist on avoiding or limiting alcohol consumption when taking medications. In the case of Advair, it is not known whether alcohol causes side effects or slows down drug effects. Advair consists of two active ingredients: fluticasone and salmeterol. Combining fluticasone and alcohol causes no adverse reaction. Salmeterol – bronchodilator – may cause increased heartbeat. Large amounts of alcohol together with salmeterol may cause chances in rapid heartbeat or tachycardia.

Reviews about Canadian Pharmacy Advair

Elliot, 16
5 5 1

The drug is excellent, fast and efficiently relieves asthma attack, although doctors say that it does not eliminate attacks, but only for prevention. To my mind it is not true. I am 16 years old, use Advair for 3 years in courses, and everything is excellent. But the most important thing is that it doesn’t build up tolerance, I recommend it to all asthmatics.
Sophie, 30
4 5 1

Almost for six years we have treated my son from bronchial asthma with all possible means. It was all unsuccessful, his cough wouldn’t go away. It was especially severe at night, closer to 4 to 5 o’clock in the morning. After we went to another attending doctor, he appointed us Advair. We are using it for a month now and there is a shift in this situation. We got rid of severe cough at night. And colds are transmitted much easier.
Louise, 26
5 5 1

My mother suffers from bronchial asthma for many years. She has tried different medicines and herbs prescribed by doctors, and herself tried to find proper medicine, but effect was little until we found Advair. After she started to receive it, attacks frequency reduced, aminophylline reception decreased. Now, my mother said that it is easier to breathe and attacks are rare now. Thanks to those who came up with this medicine! And good health to everyone!
Michael, 37
4 5 1

I suffer from asthma from 3 years old. I tried every possible medication, began to administer dexamethasone hormones 1 injection everyday. Thanks to Advair I forgot about these injections, lost almost 25 kg I gained when was using dexamethasone for 3 years. I use Advair Discus 500 mcg 2 times a day (in the morning and evening) to be on the safe side (but it is only for my personal calm) I have Ventolin in the car. I recommend it to all! I do not believe in it, but my wife categorically insisted on trying. And we didn’t have to wait long for the result.
Sarah, 22
5 5 1

I have asthma since I was 5. I suffer from attacks all my life. Only Advair Discus helped me. I already reduce dosage. Even when I get cold, there are no asthma complications. As I say, now my life is divided into Before and After Advair!