Amoxicillin

Amoxicillin
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Antibiotic, Bacterial Infections

Generic names:

Amoxycillin, Trimox, Actimoxi, Alphamox, AMK, Amoksibos, Amoxiclav Sandoz, Amoxil, Amoxin, Amoksiklav, Amoxibiotic, Amoxicilina, Apo-Amoxi, Bactox, Betalaktam, Cilamox, Curam, Dedoxil, Dispermox, Duomox, Enhancin, Gimalxina, Geramox, Hiconcil, Isimoxin, K

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What is Amoxicillin?

Amoxicillin is a broad-spectrum antibiotic used for the treatment of various bacterial infections. The drug belongs to semisynthetic antibiotics group. The antibiotic is useful in the treatment of respiratory and otolaryngological diseases such as otitis. tonsillitis, quinsy, pharyngitis, rhinitis, sinusitis.

This antibiotic is also used to treat genitourinary system diseases: pyelonephritis, prostatitis, cystitis.

The drug efficacy against infections of gastrointestinal tract and skin is clinically proved. The antibiotic has shown a positive effect in the treatment of gynecological and bile passages diseases, infectious meningitis, sepsis, for infection prevention before surgery. See a full description of Amoxicillin

Generic Version

Preparations containing amoxicillin are so numerous that it is really difficult to list all registered generics. They all have the same active ingredient. Amoxicillin generics include Amoxicillin trihydrate, Acmox, Amoxipen, Amoxilac, Amyn, Glamoxin, Hipen, Hycimox, Imox, and others.

All analogs are produced by different pharmaceutical companies, their effectiveness can vary within a very wide range (depending on active ingredient “purity”). So it is better to let your doctor or pharmacists choose the right analog.

Dosage and Instructions for Use

Any pharmaceutical form of this medication is taken orally. Reception does not depend on meals – the drug can be taken before, during, or after meals, whenever it is convenient to the patient.

The dosage for children is adjusted individually by a doctor. The daily dose depends on age, body weight, and disease severity.

Treatment duration is determined by attending physician. Average admission course lasts 5-10 days. It is not recommended to stop treatment immediately after main disease manifestations disappear – you’d better continue taking the drug for 2 more days in order to avoid disease recurrence.

Overdose

Canadian Amoxicillin does not usually cause any acute toxic effects, even at high random doses. Overdose symptoms may manifest in gastrointestinal disorders, water-electrolyte balance violation. With severe renal insufficiency, an overdose may be accompanied by signs of nephrotoxicity and crystalluria.

There is no specific antidote for amoxicillin. Treatment includes administration of activated carbon (usually there are no indications for gastric lavage) or symptomatic measures. Particular attention should be given to water-electrolyte balance. Hemodialysis is possible. Read more information about dosage and administration

Side Effects

Amoxicillin rarely causes side effects, however, in some cases, a patient can experience some negative reactions:

  • allergic reactions, skin redness, rhinitis;
  • conjunctivitis;
  • headaches;
  • sickness;
  • vomiting;
  • diarrhea;
  • abdominal pains.

Sometimes fever appears. Rarely, there are rapidly developing infectious processes caused by microorganisms resistant to this antibiotic. This is typical for debilitated patients with reduced immunity.

Contraindications

Despite the fact that Amoxicillin is the most preferred antibacterial agent, there are a number of diseases and conditions which make drug administration impossible in any case:

  • allergic diseases – asthma, atopic dermatitis, hay fever;
  • severe liver injuries or insufficiency;
  • severe dysbacteriosis;
  • infectious mononucleosis;
  • lymphocytic leukemia.

Take these pills with caution if you have chronic renal diseases and bleeding disorders. In these situations, dosage can be reduced. Continue reading about contraindications

Interactions

When you combine this antibiotic with other drugs, you should read instructions for use and consult a doctor. They can both enhance and weaken teh effects of Amoxicillin.

  • Diuretics can slow down amoxicillin clearance, thereby increasing its concentration in blood;
  • This antibiotic reduces the effectiveness of contraceptives;
  • Probenecid, phenylbutazone, oxyphenbutazone, acetylsalicylic acid, and sulfinpyrazone inhibit penicillin drugs tubular secretion, which leads to increased half-life period and amoxicillin concentration in blood plasma.;
  • The antibiotic affects only multiplying microorganisms, so it should not be administered together with antimicrobials, having bacteriostatic effect;
  • In case of positive tests for pathogen sensitivity, this antibiotic can be used in combination with other bactericidal antibiotics (cephalosporins, aminoglycosides).

Amoxicillin and Alcohol

Alcoholic drinks have a strong toxic effect on all body organs. Combined with Amoxicillin, alcohol decreases drug effectiveness because ethanol supersedes it from all organs and tissues. Drug concentration in the body abruptly decreases. If combine this antibiotic and alcohol, negative manifestations can arise from all body systems. Get more details about this interaction

Reviews
Kate, 24
5 5 1

This spring I got sick with purulent tonsillitis. Terrible thing. Very high body temperature, which is almost impossible to break. Throat aches so badly that you can not swallow anything. All this was accompanied by the fact that my son was 4 months old then, and I was breastfeeding. Doctor appointed Amoxicillin and said that during pregnancy and lactating period this medicine is completely safe. I was ready to do anything just to have relieve suffering. Half a day after taking the first pill temperature lowered and didn’t rose! The next morning I was able to more or less normally swallow. And the day after that I started gain strength again. In general, I was pleasantly surprised by Amoxicillin very fast effect. On my sun the drug had no effect, in any case, I did not notice any changes. Side effects were also absent. Great medication that is also inexpensive. “I have suffered from severe asthma attacks”
Amelia, 28
2 5 1

Last winter I got a bad cold, the doctor diagnosed bronchitis, and recommended taking Amoxicillin. The next morning, to my horror, I found severe skin redness on my face and had to run to the dermatologist, who determined hyperemia – an allergic reaction to this antibiotic. After receiving anti-allergic drugs I could get rid of skin redness and substitute Amoxicillin with another antibiotic.
George, 29
3 5 1

Good antibiotic, but like all antibiotics not without disadvantages. I was treated with it for a long time, but problems with gastrointestinal tract appeared – doctor said that it is necessary to replace antibiotic.
Luke, 25
5 5 1

I treated otitis with Amoxicillin – everything went perfectly. No side effects. Intestinal tract worked like clock, no signs of dysbacteriosis appeared. Amoxicillin struck me not only with its effect, but also with very pleasing price. For some reason it always seemed that good medicine has to be expensive. Now I know: cheap drug can be effective!
Monica, 37
5 5 1

Pediatrician appointed Amoxicillin for bronchitis, nothing else could cure my baby, although we haven’t taken any antibiotics. And then we bought children suspension and all symptoms have vanished, we were finishing course without any symptoms, although bronchitis was severe.