Priligy (Dapoxetine) from Canadian Pharmacy for premature ejaculation treatment contains highly active chemical compounds which, when combined with ethanol, cause pronounced deterioration in patient’s state of health. That is why experienced doctors warn men not to drink alcohol on the day of receiving this pharmacological agent.
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Mechanism of Interaction with Alcohol
Pharmacists claim an insufficient number of scientific works related to research of the harmful effect of alcohol in interaction with drugs. Most of the conclusions about consequences of alcohol combined with medications were made empirically.
A classic example of body’s reaction to alcoholic products is hot flushes and feeling of nausea, malaise and headaches, symptoms of food poisoning. Besides alcohol may have a detrimental effect on health in general and erectile dysfunction in particular.
The condition of expressed intoxication not only causes painful symptoms but also complicates treatment. In order to provide adequate health care, physicians must first remove intoxication, which appeared as a result of poisoning with ethyl alcohol.
After receiving alcohol the following pathological processes occur in the body:
- changes in pain threshold;
- most chemical reactions are increased, including the effect of drugs;
- increased risk of heavy internal hemorrhages, cerebral hemorrhages;
- brain cells lesions;
- oppression of respiratory system;
- increased blood pressure after vascular spasms increased the risk of hypertensive crisis and myocardial infarction;
- significantly increased blood glucose level, dangerous hypoglycemic and toxic reactions in patients with diabetes;
- the impaired secretory function of the adrenal cortex reduced production of adrenaline, cortisone and aldosterone;
- persistent heart rhythm disturbance, pain in the chest;
- increased possibility of liver cirrhosis and erosive gastritis, peptic ulcer of the gastrointestinal tract, as well as the growth of malignant tumors in the larynx, esophagus, stomach and intestines.
In view of described undesirable effects, doctors categorically forbid to take any dose of different alcohol on the background of medical therapy. Likewise, patients should do when using alcohol-containing medicinal tinctures, syrups and solutions.
Clinical Tests Data
A single dose of ethanol (0,5 g/kg, or about 2 doses) did not affect the pharmacokinetics of dapoxetine (60 mg single dose) and vice versa. Simultaneous administration of Priligy and alcohol (ethanol) may increase drowsiness and significantly reduce wakefulness during patient assessment. Receiving only ethanol and only dapoxetine does not significantly alter cognitive performance compared with placebo, but the combination of ethanol with generic analog statistically significantly changed these figures compared to only ethanol.
Concomitant administration of ethanol and this described drug increases frequency and severity of adverse reactions such as dizziness, drowsiness, slow reflexes, changes in judgment. Combination of the drug with alcohol can also enhance neuro-cardiogenic side effects, in particular, the frequency of fainting, which increases the risk of accidental injury. Therefore, patients should be advised to abstain from alcohol during treatment of premature ejaculation.
How to Use Tablets if Drink Alcohol
Having described possible negative effects after combining Priligy with alcohol, a doctor gives patient guidance on proper use of the drug. Patients suffering from various forms of erectile dysfunction undergo treatment course with Priligy (Dapoxetine), taking up to 60 mg daily. In one day no more than one light-blue pill is allowed to take.
Meals do not affect metabolization rate of active ingredients in the body of the patient. To improve drug efficiency patient has to take pills whole. Chewing or cracking pills cause loss of a large number of active chemical compounds before ingestion.
Metabolization and manifestation of the initial medicinal effect of the drug are observed during the first hour after ingestion. Maximal effect is observed within 2 hours after taking a pill. Men of reproductive age will experience increased erectile abilities during the day after taking this sexual stimulant.
Posted by Dr. Himanshu Singh