Buy Cheap Zanaflex (Tizanidine) Online: Uses, Dosage, Price and More

When it comes to managing muscle spasms and associated conditions, Zanaflex (Tizanidine) has established itself as a reliable medication that brings much-needed relief to countless individuals. Whether caused by injury, chronic conditions, or neurological disorders, muscle spasms can significantly impact one’s quality of life. Understanding the uses, dosage, and pricing of Zanaflex (Tizanidine) is crucial for those seeking effective treatment options.

In this article, we present a comprehensive guide to this medication, providing valuable insights into its uses, recommended dosage, potential side effects, and pricing considerations. We aim to equip you with the knowledge necessary to make informed decisions about this medication, empowering you to take control of your muscle spasm management.

We will explore the various medical conditions for which generic Zanaflex (Tizanidine) is prescribed, such as multiple sclerosis, spinal cord injuries, and other musculoskeletal disorders. Additionally, we will delve into the mechanism of action of this medication, shedding light on how it works to alleviate muscle spasms and enhance your overall well-being.

Understanding the appropriate dosage of tizanidine is essential to ensure its effectiveness while minimizing the risk of adverse effects. We will provide guidance on dosage recommendations and precautions to follow, highlighting the importance of consulting a healthcare professional for personalized advice.

Please note that while this article serves as a valuable resource, it is crucial to consult with a healthcare professional for personalized medical advice, diagnosis, and treatment plans. Now, let’s embark on a journey to uncover the uses, dosage, pricing, and more surrounding these pills, ensuring you have the necessary information to make informed decisions about your muscle spasm management.

What is Zanaflex (Tizanidine)?

Zanaflex, also known by its generic name Tizanidine, is a medication used to treat muscle spasms and muscle tightness. Zanaflex drug classification is centrally acting alpha-2 adrenergic agonists.

The medication works by binding to certain receptors in the brain and spinal cord, which helps to relax and reduce the excessive muscle contractions associated with muscle spasms. It acts as a muscle relaxant, providing relief from pain, stiffness, and limited movement caused by muscle spasms.

This medication is commonly prescribed for conditions such as multiple sclerosis, spinal cord injuries, and musculoskeletal disorders. It is particularly effective in managing muscle spasms that occur as a result of these conditions.

Zanaflex is available in tablet or capsule form, and the dosage may vary depending on the individual’s condition and response to treatment. It is typically taken orally, and the dosing instructions should be followed as directed by a healthcare professional.

While the pill provides relief from muscle spasms, it is important to note that it may cause drowsiness and dizziness. It is advisable to use caution when performing activities that require alertness until you understand how the medication affects you. Additionally, the drug may interact with other medications, so it is essential to inform your healthcare provider about any other drugs you are taking.

As with any medication, Zanaflex pill may have potential side effects. Common side effects may include dry mouth, weakness, fatigue, and constipation. It is important to discuss any concerns or side effects with your healthcare provider.

The drug is available as both a brand-name medication and a generic version (Tizanidine). The generic version provides a more affordable option while containing the same active ingredient as the brand-name medication.

It is crucial to follow the guidance of a healthcare professional when using these pills. They will assess your medical history, evaluate potential drug interactions, and determine the appropriate dosage for your specific needs.

What does Zanaflex do?

Zanaflex, or Tizanidine, operates by targeting the central nervous system to provide relief from muscle spasms. It functions as an agonist, binding to specific receptors in the brain and spinal cord known as alpha-2 adrenergic receptors.

When tizanidine binds to these receptors, it triggers a series of events that modulate the release of neurotransmitters in the central nervous system. By enhancing the inhibitory signals and suppressing excitatory signals, Zanaflex muscle relaxer helps reduce excessive muscle activity and promote muscle relaxation.

The activation of alpha-2 adrenergic receptors by tizanidine leads to several beneficial effects. It decreases the release of norepinephrine, a neurotransmitter associated with muscle contractions, thereby reducing the intensity and frequency of spasms. Additionally, it inhibits the transmission of pain signals, contributing to the relief of associated discomfort.

Tizanidine’s ability to modulate nerve signals in the central nervous system results in muscle relaxation, improved range of motion, and decreased muscle tone.

This allows individuals experiencing muscle spasms caused by conditions such as multiple sclerosis, spinal cord injuries, or musculoskeletal disorders to regain control and engage in daily activities more comfortably.

It is important to note that the medication’s effectiveness may vary among individuals, and the Zanaflex dosage should be determined by a healthcare professional based on factors such as the severity of spasms and individual response. The medication is typically taken orally and its effects are usually noticeable within 1 to 2 hours after administration.

While the pill provides relief from muscle spasms, it may cause side effects such as drowsiness, dizziness, and dry mouth. These effects can be managed by adjusting the dosage or timing of administration in consultation with a healthcare professional.

Understanding how the drug works sheds light on its mechanism of action and its potential to alleviate muscle spasms. However, it is crucial to consult with a healthcare professional for personalized guidance and monitoring to ensure the safe and effective use of tizanidine for your specific condition.

Zanaflex indications and uses

This medication is prescribed for several indications to address muscle spasms and improve muscle tone. The primary indications for Zanaflex uses:

  1. Multiple Sclerosis (MS): This pill is commonly prescribed for individuals with multiple sclerosis who experience muscle spasticity. It helps reduce muscle stiffness, involuntary contractions, and spasms, enhancing mobility and functional abilities.
  2. Spinal Cord Injuries: The drug is used to manage muscle spasms and tightness that can occur as a result of spinal cord injuries. It aids in relaxing the muscles, reducing pain and discomfort, and allowing individuals to engage in physical therapy and rehabilitation more effectively.
  3. Musculoskeletal Conditions: The pill is prescribed for various musculoskeletal disorders, such as low back pain or fibromyalgia, that are accompanied by muscle spasms. By promoting muscle relaxation, it helps alleviate pain, improve range of motion, and enhance overall physical functioning.
  4. Other Neurological Disorders: In certain cases, the pill may be utilized off-label for other neurological disorders characterized by muscle spasticity, such as cerebral palsy or stroke. The decision to use the pill for these conditions is typically made by a healthcare professional based on individual assessment and consideration of potential benefits.

It is crucial to note that Zanaflex pills should be used under the guidance of a healthcare professional. They will evaluate your specific condition, consider potential drug interactions or contraindications, and determine the appropriate dosage and treatment plan tailored to your needs.

Always adhere to the instructions provided by your healthcare provider and inform them of any changes in your condition or concerns you may have during the course of treatment. Regular monitoring and open communication with your healthcare professional will ensure the safe and effective use of tizanidine for your specific indications.


Here’s a table for Zanaflex (Tizanidine) dosage guidelines. Remember that these are general guidelines and the actual dose may differ based on the patient’s age, weight, other medical conditions, and response to treatment. Always consult a healthcare provider for personalized advice.

ConditionInitial DosageMaintenance DosageMaximum DosageSpecial Considerations
Muscle Spasticity in Adults2 mg orally every 6 to 8 hours as needed – not to exceed 3 doses in 24 hours2 to 4 mg orally every 6 to 8 hours, titrate in 2 to 4 mg increments to optimum effect36 mg in 24 hoursCarefully consider dose increases in elderly patients; they may have an increased risk for adverse effects
Muscle Spasticity in Children (age 6-17 years)Consult pediatricianConsult pediatricianConsult pediatricianLimited data in pediatric patients; consult pediatrician before use
Patients with Renal Impairment2 mg orally every 6 to 8 hours as neededTitrate slowly and monitor closely; reduce frequency if neededLower than normal dosingUse with caution; clearance is reduced by more than 50% in patients with renal impairment
Patients with Hepatic ImpairmentNot recommendedNot recommendedNot recommendedContraindicated in patients with liver impairment

Again, this table is provided as a general reference only. It’s crucial to consult with a healthcare provider before starting, stopping, or changing any medication regimen.

Instructions for use

Here’s how to use Zanaflex (Tizanidine) pills:

  • Strict Adherence: Make sure to use this pill as prescribed by your healthcare provider. Do not alter your dose or discontinue the medication without first consulting with your healthcare provider.
  • Method of Consumption: The medication should be ingested orally. It is recommended to consume the pill with a full glass of water. While you can take the medication with or without food, you should stick to one method consistently.
  • Dosing: Typically, the starting dose for adults suffering from muscle spasticity is 2 mg every 6 to 8 hours as necessary. Depending on your medical condition and how you react to the medication, your doctor might adjust your dosage. Nevertheless, the maximum dosage in a single day should not surpass 36 mg.
  • Scheduling: To ensure a consistent level of the medication in your body and enhance its efficacy, try to take the pills at the same times each day.
  • Preservation of the Pill: Unless your healthcare provider instructs otherwise, do not split, crush, or chew the pills. Certain versions of the medication are designed to slowly release the drug into your body, and damaging the pill could lead to a sudden release of excessive medication.
  • Handling a Missed Dose: In case you forget a dose, take it as soon as you remember. If it’s nearly time for your next dose, however, skip the missed one and stick to your regular schedule. Avoid doubling up on doses.
  • Storage Instructions: Keep the medication at room temperature, protecting it from heat, moisture, and direct light. Always keep all medications out of the reach of children.

Bear in mind, this guidance is designed to be a supplement to, not a replacement for, the knowledge and professional judgement of your healthcare provider. For information specific to your health condition and treatment, make sure to consult your healthcare provider. Your provider will give you comprehensive instructions tailored to your individual needs and circumstances.

Side effects

Like any medication, Zanaflex can have side effects, ranging from common, mild reactions to rare, severe reactions.

Common side effects:

  • Feelings of fatigue or sleepiness
  • Sensations of dizziness
  • Dryness in the mouth
  • Muscular weakness
  • Occurrence of urinary tract infections
  • Constipation
  • Abnormal results in liver function tests

These common side effects are generally mild and may lessen over time as your body becomes accustomed to the medication. If they persist or become more severe, contact your healthcare provider.

Serious side effects:

  • Experiencing hallucinations or delusions
  • States of confusion
  • Slowed heart rate
  • Feelings of faintness or lightheadedness, particularly when standing up
  • Unusual fatigue or weakness
  • The presence of dark urine
  • Yellowing of the skin or eyes, indicative of jaundice
  • Signs of an allergic reaction, such as skin rash, itching, facial or throat swelling, severe dizziness, or difficulty breathing

These serious side effects are not common but require immediate medical attention. If you experience any of these symptoms, seek medical help right away.

Keep in mind that this list may not include all potential side effects of Zanaflex. If you observe other reactions not listed here, you should inform your healthcare provider or pharmacist. They can provide you with a more comprehensive understanding and advise you on the next steps. Although the majority of individuals taking the drug do not experience serious side effects, if you have concerns about these potential side effects, it’s important to communicate with your healthcare provider. They have prescribed this medication because they believe the benefits significantly outweigh the potential risks.

Zanaflex contraindications

Zanaflex tizanidine may not be suitable for everyone. Those with a documented allergy or hypersensitivity to tizanidine or any other components of the drug should refrain from its use. Similarly, individuals with severe liver dysfunction should avoid tizanidine, as it is metabolized in the liver, and this could exacerbate their condition.

The drug also has specific interactions with certain drugs, such as fluvoxamine and ciprofloxacin, which inhibit an enzyme necessary for the breakdown of tizanidine. If these medications are being used, Zanaflex should be avoided to prevent dangerously high blood levels and potential side effects.

Patients with significantly low blood pressure, or hypotension, as well as those with kidney disease or elderly individuals may require careful dose adjustments or specific medical tests to ensure safe administration of the drug. Tizanidine has the potential to induce drowsiness or cause a drop in blood pressure, so individuals who need to remain alert or who are already managing low blood pressure should exercise caution when considering this medication.

Furthermore, women who are pregnant or breastfeeding should have a thorough discussion with their healthcare provider about potential risks before initiating Zanaflex, to protect the health of the unborn child or nursing infant. Prior to starting tizanidine, it’s critical to have a comprehensive discussion about your medical history and current medications with your healthcare provider.

Precautions and warnings

Cautionary MeasuresExplanation
Low Blood PressureZanaflex 4 mg can potentially cause low blood pressure, particularly when the dosage is escalated. Regular monitoring of blood pressure is advised for individuals using this medication.
Potential for Liver DamageThis drug could lead to liver damage, especially in patients with pre-existing liver conditions. Routine liver function tests might be required for patients on this medication.
Induced DrowsinessThis drug can lead to drowsiness, potentially affecting a person’s ability to drive or operate machinery. Individuals should avoid such activities until they are sure of how the medication impacts them.
Interactions with Alcohol and Other CNS DepressantsThe sedative properties of tizanidine can be enhanced when it is consumed along with alcohol or other central nervous system depressants. Users should be advised to steer clear of alcohol and be wary of other medications that may have a sedative effect.
Avoid Abrupt DiscontinuationSudden discontinuation of this drug may lead to withdrawal symptoms like high blood pressure and fast heart rate. Gradual reduction in dosage is recommended when discontinuing the medication.
Use During Pregnancy and LactationThe use of Zanaflex should be carefully considered during pregnancy and it should only be used if absolutely necessary. It’s unclear whether tizanidine is present in human milk, hence caution is advised when it’s administered to a breastfeeding woman.
Considerations for Elderly and Renally Impaired PatientsElderly individuals and patients with renal impairments may be more prone to the side effects of Zanaflex, which may require adjustments in the dosage.
Risk of Drug InteractionsTizanidine has the potential to interact with various other medications, which may amplify the risk of side effects or decrease its efficacy. Users should inform their healthcare providers about all other medications they are currently on.

As always, it’s vital to consult with a healthcare provider before starting any new medication. They can provide the necessary guidance based on your specific health conditions and the current medications you are using.

Interactions with other drugs

Interactions between tizanidine Zanaflex and other drugs can result in altered effectiveness of your medications and an increased likelihood of severe side effects. Notably, tizanidine can interact with medications for high blood pressure, potentially causing a further reduction in blood pressure that may lead to dizziness or fainting.

Tizanidine, being a central nervous system depressant, can enhance the effects of other CNS depressants such as alcohol, benzodiazepines, opioids, and tricyclic antidepressants. This could result in increased drowsiness or respiratory depression, thus caution should be used when these medications are being taken together with muscle relaxer Zanaflex.

In addition, certain antibiotics like ciprofloxacin and fluvoxamine can elevate the level of tizanidine in your bloodstream, potentially boosting its effectiveness and side effects. Medications such as oral contraceptives or hormone replacement therapies can also interfere with how Zanaflex is metabolized in the body, possibly leading to increased effectiveness or side effects.

Furthermore, tizanidine can interact with medications metabolized by the liver, including some statins used for managing high cholesterol, potentially leading to elevated blood levels of these medications.

It’s essential to inform your healthcare provider about all the prescription drugs, over-the-counter medications, vitamins, and herbal supplements you’re taking to avoid potential drug interactions. You should always seek advice from your healthcare provider or pharmacist before beginning, stopping, or modifying the dosage of any medications.

How to store the drug

Zanaflex should be kept in a tightly sealed container and stored at a consistent room temperature, ideally between 15 to 30 degrees Celsius (59 to 86 degrees Fahrenheit). Avoid areas with excessive heat, light, and moisture, such as the bathroom or kitchen, as these conditions may negatively affect the drug. It’s crucial to ensure the medication is stored in a safe location out of reach from children and pets. When the medication is no longer needed or has expired, don’t just throw it in the regular trash. Consult with your pharmacist or a local waste disposal facility about the correct way to dispose of the medication to ensure it doesn’t harm the environment or pose a risk to others.

Frequently asked questions

Can Zanaflex 4mg be used for long-term treatment?

A: It is generally used for short-term treatment due to its short-acting nature. Long-term usage should be discussed with your doctor to determine if it’s suitable for your condition.

Can Zanaflex cause dependency?

A: While this drug is not classified as a narcotic, abrupt cessation after long-term use can lead to withdrawal symptoms. Therefore, always consult with your doctor before stopping the medication.

Is Zanaflex safe for pregnant or breastfeeding women?

A: The safety of this drug during pregnancy or breastfeeding is unclear. If you’re pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits with your doctor.

Can Zanaflex be crushed or split?

A: Generally, these tablets should be swallowed whole. However, if you have trouble swallowing tablets, discuss alternative methods with your healthcare provider.

Can I take Zanaflex if I have kidney disease?

A: The medication is processed in the body by the liver, but kidney disease could still affect its clearance from the body. If you have kidney disease, it’s important to discuss it with your doctor before starting tizanidine.

Does Zanaflex make you sleepy?

A: Yes, it can cause sleepiness or drowsiness. If you’re affected, avoid driving or operating machinery until you know how the medication affects you.

How quickly does Zanaflex work?

A: The pill starts working within one to two hours after ingestion. Its effects last for three to six hours.

What should I do in case of an overdose?

A: If you suspect an overdose of Zanaflex, seek immediate medical attention. Symptoms may include severe drowsiness, slow heartbeat, fainting, or difficulty breathing.

Are there any dietary restrictions when taking Zanaflex 2mg?

A: There are no specific foods that you must avoid when taking these pills. However, this medication may be taken with or without food, but it’s important to be consistent with how you take it to maintain stable drug levels in the body.

Fflexeril vs Zanaflex: what is the difference?

Flexeril (cyclobenzaprine) and Zanaflex (tizanidine) are both muscle relaxants, but they have different chemical structures, mechanisms of action, and uses. Cyclobenzaprine works primarily in the brain stem to reduce muscle tone, and is often used for muscle spasms associated with acute musculoskeletal conditions, such as muscle strains. On the other hand, tizanidine acts primarily on the central nervous system to reduce muscle tone, and it is used to treat muscle spasticity, which is often a result of chronic conditions such as multiple sclerosis or spinal cord injury.

In terms of side effects, cyclobenzaprine may cause more dry mouth and tizanidine may lower blood pressure more than cyclobenzaprine. Additionally, tizanidine is typically shorter-acting than cyclobenzaprine. The choice between the two often depends on the specific patient’s condition, other medications they are taking, and their overall health status.

Is Zanaflex a controlled substance?

No, this medication is not classified as a controlled substance by the United States Drug Enforcement Administration (DEA).

How long does Zanaflex stay in your system?

Tizanidine has a relatively short half-life of about 2.5 hours, which is the time it takes for half of the drug to be eliminated from your body. Given this, it can take roughly 13.5 to 15 hours for the drug to be largely eliminated from your system. However, this can vary depending on factors like your metabolism, age, and overall health, and traces of the medication may remain in the body for longer.

Can I use Zanaflex for anxiety?

This drug is not typically used for treating anxiety. It’s a muscle relaxant, primarily used for treating muscle spasticity associated with conditions like multiple sclerosis or spinal cord injury. While it has a sedative effect, which might seem like it could help with anxiety, it is not approved or recommended for this purpose. If you’re experiencing anxiety, it’s best to consult with a healthcare provider who can recommend appropriate treatments, which could include medication, therapy, or lifestyle changes.

Does Zanaflex make you sleepy?

Yes, the pill can often cause drowsiness or sleepiness, which is a common side effect due to its muscle-relaxing action in the central nervous system.

Is Zanaflex addictive?

This medication is not typically classified as addictive in the way some substances, like opioids or benzodiazepines, can be. However, it’s important to note that physical dependence can develop with long-term use. This means that if the medication is abruptly stopped, withdrawal symptoms such as high blood pressure, a fast heart rate, tremors, and anxiety may occur. Therefore, it’s always advised to taper off the medication under the supervision of a healthcare provider rather than stopping it abruptly.

Does Zanaflex show up on a drug test?

This medication is not a substance that is typically screened for in standard drug tests, such as those looking for illicit substances like opioids, cannabis, or amphetamines. However, it’s always a good idea to disclose all medications you’re taking to the test administrator to account for any potential anomalies in the results.

What is Zanaflex cost?

The current cost for Zanaflex (tizanidine) could range from around $10 to $50 for a supply of 30 tablets, depending on the dosage. However, prices can vary widely based on location, pharmacy, and insurance coverage. Therefore, it’s recommended to check with your local pharmacy or use an online tool to get the most current prices for this medication.

Is Zanaflex a strong muscle relaxer?

Yes, the drug is considered a potent muscle relaxant, often used to manage spasticity caused by conditions such as multiple sclerosis or spinal cord injuries.

How long does Zanaflex last?

This drug is a short-acting muscle relaxer. Its effects typically begin within an hour of oral administration and generally last between three to six hours. However, the duration can vary depending on individual factors such as metabolism and overall health.

How does Zanaflex work?

It works by blocking nerve impulses sent to the brain that cause muscle contraction, leading to muscle relaxation and a decrease in muscle spasticity.

How often can you take Zanaflex?

The frequency of taking these pills can vary, but it is typically taken up to three times a day as needed, according to the specific instructions provided by your healthcare provider. It’s important to follow your doctor’s instructions precisely and not to take more than the recommended dose.

How does Zanaflex make you feel?

This drug is a muscle relaxant, and it can make you feel relaxed and possibly drowsy due to its effects on the central nervous system. However, it can also cause side effects such as dizziness, dry mouth, and fatigue, which can contribute to a general feeling of being unwell or “off.”

Zanaflex reviews

“This pill has been great for my muscle spasms. It’s effective and fast-acting. I do experience some dizziness, but it’s manageable and worth the relief I get.” – Allen K.

“The medication definitely helps with my muscle stiffness, but it causes a bit of sleepiness. I have learned to take it only at night. It does help me sleep better, though.” – Sandra O.

“Zanaflex medication has been a significant help in managing my fibromyalgia symptoms. I’m finally able to relax my muscles and get some relief from the constant pain.” – Aaron B.

“While the medicine is very effective for muscle spasms, I did experience low blood pressure. My doctor and I are monitoring it closely. It’s a fair trade-off for the relief I get.” – Debra R.

“I’ve been on this medication for three months now and the difference is night and day. My muscle spasms have significantly decreased and I’m finally getting a good night’s sleep.” – Cheryl T.

“it works well to control my muscle spasms, but it also makes me feel very drowsy. I find that taking it at night works best for me.” – Martin W.

“The pill has been very helpful in managing my muscle spasticity. It’s fast-acting and I’m able to function normally now. The only downside is that it does make my mouth very dry.” – Rebecca S.

“Zanaflex dosage 8 mg is a lifesaver! I was struggling with severe muscle spasms due to my MS, but this medicine has changed that. I can now live my life with far less pain and discomfort.” – Patricia F.

“I’ve been taking these pills for my muscle spasms for a few weeks now. The medication is effective, but it does lower my blood pressure so I have to be careful.” – Roger C.

“I can’t say enough about how much this medication has helped me. My muscle spasms are under control and I’m able to sleep better at night. The relief I’ve gotten is worth the minor side effects.” – Brenda J.

Disclaimer: This article is about a drug used to treat erectile dysfunction. It is important to note that this drug should only be taken under the supervision of an approved drug. The Silagra information provided herein is for educational purposes only and is not a substitute for professional medical advice, diagnosis or treatment. Consult your doctor before taking any medication.