Cipro (Ciprofloxacin)

Cipro
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Antibiotics
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Infections, Antibiotic, Urinary Tract Infections, Cystitis, Prostatitis, Sinusitis, Diarrhea, Typhoid Fever, Gonorrhea, Pyelonephritis

Generic names:

Ciprofloxacin, Ciloxan, Ciproxin, Proquin

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What is Cipro?

Cipro is a modern antibiotic that belongs to the fluoroquinolone group. This drug has its own special characteristics. Its action is quite rapid if compared to similar drugs.

The drug is based on its detrimental effects on bacterial cells: inhibits DNA formation and division (genetic apparatus), suppress bacteria growth and causes structural changes in microorganisms. It is active against the following microorganisms: Staphylococcus, Streptococcus, Brucella, Haemophilus influenzae, Legionella, Moraxella, Neisseria, Salmonella, Shigella, Enterococcus, Escherichia coli, Klebsiella, Morganella, Proteus, Pseudomonadaceae.

Canadian Cipro covers gram-positive and gram-negative aerobic and anaerobic organisms. It is successfully used to treat systemic infections: respiratory tract, ENT, eyes, urinary tract and gynecological infections, sexually transmitted diseases, including gonorrhea, abdominal and gastrointestinal tract, skin and soft tissues infections, osteomyelitis, septic arthritis, peritonitis, sepsis, septicemia. Read more about Cipro…

Generic Versions

The brand-name version of the medication was created in 1987 and included in WHO’s List of Essential Medicines. The drug has many generic versions that have the same quality and active ingredient but cost much less. These are Baycip, Cifran, Ciloxan, Cipract, Ciprofloksacin, Ciprofloxacina, Ciprofloxacinum, Ciprofloxin, Ciprowin, Ciproxin, Ciproxina, Ciriax, Floxelena, Kensoflex, Lucipro, Novidat, and so on. Canadian Pharmacy is selling the cheapest generic versions of this drug.

Dosage and Instructions

This medication should be taken every 12 hours, with a large amount of fluid (water)

  • For adults, the average Cipro dosage is 250-500 mg 2 times a day. If necessary, a single dose can be increased to 750 mg.
  • In respiratory and urinary complicated tract infections, the drug is used at a dosage of 250-500 mg every 12 hours, for severe cases – up to 750 mg every 12 hours.
  • In uncomplicated urinary tract infections, Cipro is prescribed at a dosage of 250 mg, joints and bones infections – 500-750 mg, gastrointestinal infections – 250-500 mg, gynecological infections – 500 mg every 12 hours.
  • In case of acute uncomplicated gonorrhea, 250 mg is used.

The duration of therapy duration depends on disease severity and course. Typically, the treatment course lasts 7-14 days. As a rule, after symptoms disappear and body temperature normalizes, the treatment lasts 2-3 days. For joints and bones infections, the treatment course may last for 4-6 weeks, osteomyelitis – 2 month.

Patients suffering from renal insufficiency need to adjust the required dose and an interval between doses.

Overdose

An excessive dose of Cipro may cause the following negative symptoms:

  • fainting;
  • sickness;
  • headaches;
  • vomiting;
  • convulsions, etc.

Treatment: no specific antidote is known. It is necessary to carefully monitor patient’s condition and conduct a gastric lavage, routine emergency measures, to ensure adequate intake of fluid. With hemodialysis or peritoneal dialysis, only minor (less than 10%) amount of drug can be cleared.

Side Effects

Common side effects of Cipro: 

  • dizziness;
  • sickness;
  • abdominal pains;
  • diarrhea;
  • flatulence;
  • vomiting;
  • headaches;
  • agitation;
  • tremor.

In rare cases, a patient can experience there arterial hypertension, itching, rashes, sweating, sensitivity peripheral disorders, hot flashes, increased intracranial pressure, fear, depression, visual disorders, hepatitis, tachycardia.

In extremely rare cases, a person can feel bronchospasm, angioedema, arthralgia, anaphylactic shock, vasculitis, petechiae, Lyell’s syndrome, Stevens-Johnson’s syndrome, anemia, leukopenia, eosinophilia, hemolytic anemia, thrombocytopenia, increased bilirubin, increased creatinine, increased alkaline phosphatase, liver transaminases.

Contraindications

Absolute contraindications to Cipro:

  • hypersensitivity to drug components;
  • inflammation of the tendon;
  • myasthenia gravis;
  • peripheral neuropathy;
  • kidney impairment;
  • allergies to quinolones;
  • lung transplant, kidney transplant, heart transplant;
  • severe hepatic/renal insufficiency;
  • pseudotumor cerebri;
  • previous tendinitis, which appeared due to quinolones use;
  • seizures;
  • the lactation period, pregnancy;
  • low amount of potassium in the blood;
  • rapid or slow heartbeat;
  • age under 12.  See a full list of contraindications…

Interactions

  • Simultaneous administration of theophylline and Cipro can increase theophylline concentration in blood and increase its half-life period;
  • Antibiotic clearance is reduced by probenecid;
  • Antacids containing aluminum hydroxide and/or magnesium hydroxide can slow down drug absorption. This reduces ciprofloxacin
    concentration in urine and blood plasma. Consequently, an interval between these drugs must be at least 4 hours;
  • The antibiotic may potentiate coumarin anticoagulants effect. See a full list of interactions…

Cipro and Alcohol

This drug is often used together with alcohol. Of course, a lot of people simply cannot refrain from the bad habit of drinking alcohol even during treatment and when taking antibiotics. But the combination of this drug with strong alcoholic drinks can be very detrimental to health. Learn the consequences of combining Cipro and alcohol…

Reviews
Maya, 24
5 5 1

Many people know how it is unpleasant to suffer from back pains. Often the cause is kidney disease. Previously, doctors prescribed courses of vitamins injections, antibiotics and so on. But now, thanks to the broad-spectrum antibiotic Cipro, injections are no longer prescribed. Cipro is taken 2 times a day, in the morning and evening. One pill contains 500 mg of ciprofloxacin hydrochloride. Also, it can be used at respiratory, ENT, genitals and digestive system diseases. In case of my disease it helped. I’m glad that I did not have to undergo endless injections course.
Richard, 41
5 5 1

I took Cipro, it helps well at all ENT diseases and causes no side effects. Thanks to Cipro I effectively and quickly treated my health problems!
Rachel, 28
4 5 1

I modern world, we can’t live without antibiotics. Of course, you shouldn’t use them without a doctor’s prescription, it is really dangerous for health. But, if it is prescribed, you have to take them. I was recently prescribed Cipro for 5 days course. I do not really want to go into details, but the reason is the following: I have painful skin problems on my face. Feeling dreadful, I was very afraid that it would inflame, and doctor advised me one very expensive antibiotic, to which I asked, if there was some sort of analogue. I didn’t want to spend hundreds of dollars on such a matter. The doctor then suggested taking Cipro and explained that, in fact, it is all the same, what to take, but expensive drug effect lasts longer.
Lydia, 33
4 5 1

I use this antibiotic not for the first time. I used to buy more expensive medications, but now I see that composition is the same, but the price is different in by several times. For my chronic pyelonephritis I often have to buy such drugs from season to season. If compare this drug and others antibiotics of this type, side effects are the same, composition and drug description are the same, but the price is different. Therefore, I see no reason to pay more. But the drug helped me very much with my inflammation. I also apply it for cystitis, although there is a slightly different reception scheme.
Jordan, 27
3 5 1

Since childhood I suffer from chronic tonsillitis (i. e. quinsy), I was always prescribed antibiotics. I have tried numerous drug, but few helped. Last time the doctor prescribed me Cipro pills. It is a broad spectrum antibiotic, very famous and popular and time-tested. The effect was remarkable. After two days of application quinsy disappeared. But full antibiotic course is at least 7 days! Negative aspects are only side effects: intestinal disorders and disbacteriosis. But all this is easily to treat. Yet it should be noted that Cipro should not be used at children under 12 years old, pregnant and lactating women.
Hollie, 29
5 5 1

Since childhood I often suffered from bronchitis, well-known disease with a terrible cough. Eventually I was diagnosed chronic bronchitis. I have tried all possible remedies during these years, however all was useless, cough lasted during months! Then I started to try everything I could find and found a good inexpensive Cipro antibiotic. After 2 days of administration my cough vanished; now as bronchitis comes I always keep it close at hand! By the way it is very effective at reproductive system diseases too, it helps with urethralgia for example – one or two pills is all that is required. But you should not abuse it because it’s a very strong antibiotic!