Buy Generic Neurontin (Gabapentin) Online – Indications, Dosage, Side Effects, Contraindications, Pricing, Reviews

What is Neurontin?

Neurontin is the brand name for the medication gabapentin, which is an anticonvulsant drug primarily used to treat epilepsy. It is also prescribed for the management of neuropathic pain, which is caused by damage to the nerves. Gabapentin is believed to work by affecting the transmission of certain chemicals in the brain that are involved in seizures and pain signals.

While initially approved by the U.S. Food and Drug Administration (FDA) for the treatment of epilepsy, Neurontin is commonly prescribed off-label for other conditions such as restless leg syndrome, fibromyalgia, hot flashes, and certain mood disorders. However, it’s important to note that the effectiveness of gabapentin for these off-label uses varies, and the use of any medication should always be discussed with a healthcare professional.


Neurontin, or gabapentin, is classified as an anticonvulsant or antiepileptic drug (AED). Let’s delve into its classification and related details:

  1. Drug Class: Gabapentin belongs to the class of medications known as anticonvulsants or antiepileptic drugs. Anticonvulsants are a group of medications primarily used to treat seizures or epilepsy. They work by stabilizing the electrical activity in the brain, preventing abnormal and excessive firing of neurons.
  2. Mechanism of Action: The precise mechanism of action of gabapentin is not fully understood. However, it is believed to exert its therapeutic effects through several mechanisms:
    • Binding to α2δ Subunit of Voltage-Gated Calcium Channels: Gabapentin binds to the α2δ subunit of voltage-gated calcium channels in the central nervous system. This binding reduces the influx of calcium into nerve terminals, resulting in decreased release of neurotransmitters such as glutamate, norepinephrine, and substance P. By modulating the release of these neurotransmitters, gabapentin helps in controlling seizures and reducing pain signals in neuropathic pain conditions.
    • GABAergic Effects: Gabapentin also enhances the synaptic concentration of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the brain. It is believed to increase the synthesis and release of GABA, leading to an overall increase in GABAergic activity. This enhanced GABAergic effect contributes to the anticonvulsant properties of gabapentin.
  3. Off-Label Uses: In addition to its approved indications, gabapentin is sometimes prescribed off-label (i.e., for conditions not officially approved by regulatory authorities) for various conditions, including:
    • Restless Leg Syndrome (RLS): Gabapentin may be used to alleviate the uncomfortable sensations and urge to move associated with RLS.
    • Fibromyalgia: It is sometimes prescribed to help manage the chronic pain and associated symptoms of fibromyalgia.
    • Mood Disorders: Gabapentin may be used off-label to help stabilize mood in conditions such as bipolar disorder and anxiety disorders.

What is neurontin generic name?

The generic name of this drug is indeed gabapentin. Here are some details about gabapentin:

  1. Chemical Structure: Gabapentin is a structural analogue of the neurotransmitter gamma-aminobutyric acid (GABA). However, it does not directly bind to GABA receptors in the brain.
  2. FDA Approval: Gabapentin was first approved by the U.S. Food and Drug Administration (FDA) in 1993 under the brand name Neurontin. It was initially approved as an adjunctive treatment for partial seizures in adults with epilepsy.
  3. Off-Label Use: Although initially approved for epilepsy, gabapentin is frequently prescribed off-label for various conditions, such as neuropathic pain, restless leg syndrome, fibromyalgia, and certain mood disorders. Off-label use refers to the practice of using a medication for an indication not specifically approved by regulatory authorities.
  4. Pharmacokinetics: Gabapentin is well-absorbed orally, and its bioavailability is not significantly affected by food intake. The drug reaches peak plasma concentrations within 2 to 3 hours after administration. Gabapentin does not bind extensively to plasma proteins and has a relatively long elimination half-life, typically ranging from 5 to 7 hours in adults.
  5. Dosage Forms and Strengths: Gabapentin is available in various dosage forms, including capsules, tablets, and oral solutions. The strength of gabapentin can vary, with common strengths ranging from 100 mg to 800 mg per dosage unit. The prescribed dosage and frequency depend on the specific condition being treated and individual patient factors.
  6. Side Effects: Gabapentin may cause certain side effects, although their occurrence and severity can vary among individuals. Common side effects include drowsiness, dizziness, fatigue, coordination problems, gastrointestinal discomfort (such as nausea and diarrhea), and visual disturbances. It is essential to report any concerning side effects to a healthcare professional.
  7. Discontinuation and Withdrawal: Abruptly stopping gabapentin after prolonged use may result in withdrawal symptoms, including anxiety, insomnia, nausea, sweating, and flu-like symptoms. Therefore, it is generally recommended to gradually taper the dosage under medical supervision when discontinuing gabapentin.

What is Neurontin used for?

Gabapentin, is used for various medical conditions. The approved Neurontin indications include:

  1. Epilepsy: It is prescribed as an adjunctive (add-on) treatment for partial seizures in adults and children aged 3 years and older with epilepsy. It can be used alongside other antiepileptic drugs or as monotherapy.
  2. Neuropathic Pain: It is approved for the management of neuropathic pain. This includes conditions such as postherpetic neuralgia (nerve pain that persists after a shingles infection), diabetic neuropathy (nerve damage due to diabetes), and peripheral neuropathy (nerve damage in the hands or feet).

It’s important to note that this drug is also prescribed off-label for other conditions, which means its use is not officially approved by regulatory authorities but has been found to be beneficial in certain cases. Some off-label uses include:

  1. Fibromyalgia: It may be prescribed to help manage the chronic pain and associated symptoms of fibromyalgia, a disorder characterized by widespread musculoskeletal pain, fatigue, and tenderness.
  2. Restless Leg Syndrome (RLS): The describe drug can be used off-label to alleviate the uncomfortable sensations and urge to move that are characteristic of restless leg syndrome.
  3. Anxiety Disorders: In some cases, Neurontin may be prescribed off-label to help manage anxiety disorders, including generalized anxiety disorder and social anxiety disorder.
  4. Bipolar Disorder: Neurontin may be used as an adjunctive treatment in individuals with bipolar disorder to help stabilize mood and manage certain symptoms.

How does Neurontin work?

Neurontin (gabapentin) exerts its pharmacological effects through a complex mechanism of action. While the exact mechanism is not fully understood, several hypotheses have been proposed:

  1. Modulation of Calcium Channels: This drug is thought to bind to the α2δ subunit of voltage-gated calcium channels in the central nervous system. This binding results in a reduction in the influx of calcium into nerve terminals. By modulating calcium channels, Neurontin may decrease the release of several neurotransmitters, including glutamate, norepinephrine, and substance P. This modulation of neurotransmitter release contributes to the drug’s anticonvulsant and analgesic effects.
  2. Enhanced GABAergic Activity: This medication has been found to increase the synthesis and release of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the brain. While this product does not directly bind to GABA receptors, its actions result in an overall increase in GABAergic activity. This enhanced GABAergic effect may contribute to the drug’s anticonvulsant properties.
  3. Altered Neurotransmitter Signaling: It may modulate the release and activity of other neurotransmitters, such as glutamate, which is an excitatory neurotransmitter. By reducing glutamate release and excitatory signaling, Neurontin may help dampen excessive neuronal activity and reduce seizure activity.

How long does it take Neurontin to work?

The time it takes for Neurontin (gabapentin) to start working can vary depending on the individual and the condition being treated. Here are some general guidelines:

  1. Epilepsy: When Neurontin is used as an adjunctive treatment for partial seizures in epilepsy, it may take a few days to weeks to see the full effects. The dosage is typically started at a low level and gradually increased over time to the optimal therapeutic dose. The response to treatment can vary, and it may require several weeks to determine the effectiveness ofthe drug in seizure control.
  2. Neuropathic Pain: In the case of neuropathic pain, the time it takes for Neurontin to provide relief can also vary. Some individuals may experience a reduction in pain within a few days, while others may require several weeks of treatment before experiencing noticeable benefits. It is important to note that it may provide gradual and cumulative pain relief over time, and the full effects may be achieved after a few weeks of treatment.

How long does Neurontin stay in your system?

The elimination half-life of Neurontin (gabapentin) is approximately 5 to 7 hours in adults. The half-life refers to the time it takes for the concentration of a drug in the body to decrease by half. Based on the half-life, it is estimated that it takes about 1-2 days for Neurontin to be eliminated from the body.

However, it’s important to note that individual factors such as age, kidney function, and overall health can affect the elimination of this drug from the system. In individuals with impaired kidney function, the clearance of gabapentin may be decreased, resulting in a longer elimination time.

Additionally, the effects of Neurontin may continue for some time even after it has been cleared from the body, as its pharmacological effects may persist for a period after the last dose. The duration of these effects can vary depending on factors such as dosage, duration of treatment, and individual response.

What is the dosage?

The dosage of Neurontin (gabapentin) can vary depending on the condition being treated, the individual patient, and other factors. Here are some general guidelines for the min and max doses of Neurontin:

  1. Epilepsy:
    • Min Dose: The minimum starting dose in the treatment of epilepsy is typically 300-900 mg per day, divided into three doses.
    • Max Dose: The maximum recommended dose in the treatment of epilepsy is usually 3600 mg per day, although some individuals may require higher doses under medical supervision.
  2. Neuropathic Pain:
    • Min Dose: The minimum starting dose in the management of neuropathic pain is typically 300 mg per day, divided into three doses.
    • Max Dose: The maximum recommended dose in the treatment of neuropathic pain is usually 3600 mg per day. However, doses above 1800 mg per day may not provide additional benefits for most individuals.


An overdose of Neurontin (gabapentin) occurs when a person takes a higher dose of the medication than prescribed or intended, resulting in potentially harmful effects. Overdose can happen due to various reasons, including accidental ingestion of multiple doses or intentional misuse of the drug.

Symptoms of an overdose can vary depending on the amount taken and individual factors but may include drowsiness, dizziness, unsteadiness, double vision, slurred speech, and difficulty breathing. In severe cases, it can lead to respiratory depression, loss of consciousness, and even coma.

To avoid complications from overdose, it’s essential to take the following preventive measures:

  1. Follow Prescribed Dosage: Take the drug exactly as prescribed by your healthcare professional. Do not exceed the recommended dose or alter the dosing schedule without medical guidance.
  2. Communicate with Healthcare Provider: Inform your healthcare provider about all medications you are currently taking, including prescription drugs, over-the-counter medications, and any herbal or dietary supplements. Some medications or substances can interact with Neurontin pill and increase the risk of adverse effects.
  3. Be Mindful of Medical Conditions: Inform your healthcare provider about any medical conditions you have, especially kidney problems or respiratory issues. Certain medical conditions can affect the clearance of the substance from the body and increase the risk of overdose.
  4. Store Medication Safely: Keep all medications out of the reach of children and pets. Store them in a secure location, away from excessive heat, moisture, and direct sunlight.

What are contraindications?

Neurontin (gabapentin) has several contraindications, which are specific situations or conditions in which the use of the medication is not recommended due to potential risks. Here are some contraindications associated with this medication:

  1. Hypersensitivity: The very drug is contraindicated in individuals who have a known hypersensitivity or allergy to gabapentin or any of the components of the formulation. Allergic reactions can range from mild skin rashes to severe allergic reactions, including anaphylaxis.
  2. Previous Hypersensitivity Reaction: It should not be used in individuals who have experienced a previous hypersensitivity reaction, such as Stevens-Johnson syndrome or toxic epidermal necrolysis, while taking gabapentin.

Additionally, certain precautions and considerations should be taken into account before using Neurontin. These include:

  1. Renal Impairment: It is primarily eliminated through the kidneys, so caution should be exercised in individuals with renal impairment. Dosage adjustments may be necessary in patients with impaired renal function.
  2. Drug Interactions: It can interact with other medications, including those affecting renal function or CNS depressants, such as opioids or benzodiazepines. Inform your healthcare provider about all medications you are taking to assess potential interactions.
  3. Geriatric Population: Elderly individuals may be more susceptible to the side effects of Neurontin, such as dizziness and drowsiness. Lower initial doses and careful monitoring may be required in this population.
  4. Pregnancy and Lactation: It should be used during pregnancy or breastfeeding only if the potential benefits outweigh the potential risks. Consult a healthcare professional for a thorough evaluation of the risks and benefits in these situations.

What are the side effects?

Neurontin (gabapentin) can cause various side effects in individuals taking the medication. It’s important to note that not everyone will experience these side effects, and their severity and frequency can vary. Here are some common side effects associated with thi preparation:

  1. Central Nervous System (CNS) Effects:
    • Drowsiness;
    • Dizziness;
    • Fatigue;
    • Headache;
    • Impaired coordination or unsteadiness;
    • Tremor;
    • Difficulty concentrating or memory problems;
    • Abnormal thinking or confusion.
  2. Gastrointestinal Effects:
    • Nausea;
    • Vomiting;
    • Diarrhea;
    • Abdominal pain;
    • Dry mouth;
  3. Visual Disturbances:
    • Blurred vision;
    • Double vision (diplopia);
    • Abnormal eye movements (nystagmus).
  4. Peripheral Edema: Swelling of the extremities, particularly the ankles and feet.
  5. Weight Gain: Some individuals may experience weight gain while taking Neurontin.
  6. Mood and Behavior Changes:
    • Mood swings;
    • Agitation or irritability;
    • Anxiety;
    • Depression;
    • Suicidal thoughts or behaviors (rare, but important to monitor, especially in individuals with a history of mental health conditions).
  7. Allergic Reactions: While rare, allergic reactions to Neurontin can occur, and they may present as skin rashes, hives, itching, or swelling of the face, lips, tongue, or throat. Severe allergic reactions like anaphylaxis are very rare.

What are drug interactions?

Neurontin can interact with other medications, altering their effects or increasing the risk of side effects. It’s important to inform your healthcare provider about all medications you are taking, including prescription drugs, over-the-counter medications, and supplements. Here are some notable drug interactions associated with Neurontin:

  1. CNS Depressants: Gabapentin may enhance the effects of medications that act as central nervous system (CNS) depressants, such as opioids, benzodiazepines, sedatives, and alcohol. Concurrent use of these medications with Neurontin can lead to increased sedation, drowsiness, and respiratory depression.
  2. Antacids: Taking the described drug with antacids containing aluminum or magnesium hydroxide may decrease the absorption of gabapentin. It is recommended to separate the administration of Neurontin and antacids by at least 2 hours.
  3. Opioids: There have been reports of respiratory depression and sedation when Neurontin is taken concurrently with opioids. Caution should be exercised, and dosage adjustments may be necessary when using these medications together.
  4. Antiepileptic Drugs (AEDs): Gabapentin can interact with other antiepileptic drugs, such as phenytoin, valproic acid, and carbamazepine, altering their blood levels and potentially increasing the risk of side effects or reducing efficacy. Dosage adjustments and close monitoring may be required when Neurontin is used concomitantly with other AEDs.
  5. Morphine: Concurrent use of Neurontin and morphine may increase the absorption of gabapentin, resulting in increased blood levels of the drug. Monitoring for increased side effects and adjusting the dosage may be necessary.
  6. Diuretics: Neurontin may interact with certain diuretics, such as hydrochlorothiazide, affecting electrolyte balance and increasing the risk of dehydration. Close monitoring of electrolyte levels and renal function is advised when using these medications together.

What are withdrawal symptoms?

Abruptly stopping or rapidly decreasing the dosage of Neurontin (gabapentin) after prolonged use can potentially lead to withdrawal symptoms. These symptoms can vary in severity and duration among individuals. Common withdrawal symptoms associated with Neurontin may include:

  1. Anxiety: Increased feelings of worry, restlessness, or unease.
  2. Insomnia: Difficulty falling asleep or staying asleep.
  3. Nausea and/or Vomiting: Feelings of queasiness and the urge to vomit.
  4. Sweating: Excessive sweating or night sweats.
  5. Flu-Like Symptoms: Symptoms similar to those of the flu, such as body aches, chills, and feverishness.
  6. Gastrointestinal Distress: Digestive symptoms like diarrhea, stomach cramps, or abdominal discomfort.
  7. Mood Changes: Emotional fluctuations, irritability, or mood swings.

Gabapentin vs Neurontin

Generic NameGabapentinGabapentin
Brand NameNot applicableNeurontin
Indications– Epilepsy– Epilepsy
– Neuropathic pain– Neuropathic pain
– Off-label uses:– Off-label uses:
– Restless Leg– Restless Leg
– Fibromyalgia– Fibromyalgia
– Anxiety disorders– Anxiety
– Bipolar disorder– Bipolar disorder
MechanismModulation of calciumModulation of
of Actionchannels, enhancementcalcium channels,
of GABAergic activityenhancement of
and alteredGABAergic activity
Dosage FormsCapsules, tablets,Capsules, tablets,
oral solutionoral solution
Common Side– Drowsiness– Drowsiness
Effects– Dizziness– Dizziness
– Fatigue– Fatigue
– Gastrointestinal– Gastrointestinal
– Visual disturbances– Visual
previous hypersensitivityprevious
reaction to gabapentinhypersensitivity
Drug InteractionsCNS depressants,CNS depressants,
antacids, opioids,antacids, opioids,
antiepileptic drugs,antiepileptic
morphine, diureticsdrugs, morphine,
WithdrawalAbrupt cessation orAbrupt cessation or
Symptomsrapid dose reductionrapid dose
of gabapentin mayreduction of
lead to withdrawalgabapentin may
symptoms such aslead to withdrawal
anxiety, insomnia,symptoms such as
nausea, sweating,anxiety, insomnia,
flu-like symptoms,nausea, sweating,
gastrointestinalflu-like symptoms,
distress, moodgastrointestinal
changesdistress, mood

Neurontin pricing

We can provide some general pricing information for Neurontin (gabapentin) based on historical data. However, please note that these prices can vary and may not reflect the current rates. It is always best to check with local pharmacies or online resources for up-to-date pricing information. Here are approximate price ranges for this drug:

  1. Branded Neurontin: The cost of branded Neurontin can vary depending on the dosage strength and quantity. As of my last knowledge update in September 2021, the average retail price for a 90-day supply (at a dosage of 300mg) ranged from $200 to $400 in the United States.
  2. Generic Gabapentin: Generic versions of gabapentin tend to be more affordable than the branded Neurontin. The average retail price for a 90-day supply (at a dosage of 300mg) of generic gabapentin ranged from $20 to $80 in the United States.

These price ranges are approximate and can vary significantly based on factors such as location, pharmacy, dosage strength, and any available discounts or insurance coverage. It is advisable to check with local pharmacies or online resources for the most accurate and up-to-date pricing information specific to your location and circumstances.


Q: Why is Neurontin a controlled substance?

A: Neurontin (gabapentin) is not classified as a controlled substance at the federal level in the United States. However, it is important to note that some states have implemented regulations to classify this drug as a controlled substance, typically Schedule V or Schedule IV. These state-level regulations aim to monitor and control the prescribing and dispensing of this substance due to its potential for misuse and abuse.

Neurontin is not considered a narcotic. Narcotics, also known as opioids, are a specific class of drugs that act on opioid receptors in the brain. Neurontin, on the other hand, is an anticonvulsant or antiepileptic medication that works through different mechanisms of action.

While it is not considered highly addictive, it is possible for individuals to develop physical dependence or experience withdrawal symptoms upon abrupt discontinuation after prolonged use. Discontinuing gabapentin should be done gradually and under medical supervision to minimize the risk of withdrawal symptoms. It is important to follow the prescribed dosage and consult with a healthcare professional regarding any concerns about addiction or dependence.

Q: Neurontin for dogs – yes or no?
A: Neurontin (gabapentin) is sometimes prescribed for dogs by veterinarians for certain medical conditions. While this drug is primarily approved for use in humans, it can also be used in veterinary medicine under veterinary guidance and prescription.

In dogs, Neurontin may be prescribed for the following conditions:

  1. Seizure Disorders: It can be used as an adjunctive treatment for dogs with epilepsy or seizure disorders to help control seizures when other antiepileptic medications are insufficient.
  2. Neuropathic Pain: It may be prescribed for dogs experiencing neuropathic pain, which can occur as a result of nerve damage, spinal cord injury, or certain medical conditions.
  3. Anxiety or Behavioral Disorders: It can sometimes be used off-label to help manage anxiety or certain behavioral disorders in dogs, although other medications or behavioral interventions may be preferred in these cases.

Q: Is neurontin a good painkiller?

A: Neurontin (gabapentin) can be effective as a painkiller for certain types of pain, particularly neuropathic pain. Neuropathic pain is caused by damage or dysfunction of the nerves, and it works by modulating the transmission of pain signals in the central nervous system.

This drug has been shown to be effective in managing various neuropathic pain conditions, including postherpetic neuralgia (nerve pain that persists after a shingles infection), diabetic neuropathy (nerve damage due to diabetes), and peripheral neuropathy (nerve damage in the hands or feet).

Q: Does Neurontin make you sleepy?

A: Yes, Neurontin (gabapentin) can cause drowsiness and sedation as a common side effect. Many individuals experience increased sleepiness or drowsiness when taking this medicine. This side effect is more prevalent when starting the medication or when the dosage is increased.

Q: Neurontin vs alcohol

A: Combining Neurontin (gabapentin) with alcohol is generally not recommended due to the potential for increased side effects and risks. Both substances can have sedative effects on the central nervous system (CNS), and when taken together, their effects can be additive or synergistic.

Q: Does neurontin cause weight gain?

A: Yes, weight gain can be a potential side effect of Neurontin (gabapentin). While not everyone will experience weight gain while taking Neurontin, it has been reported as a common side effect.

The exact mechanism by which Neurontin can contribute to weight gain is not fully understood. However, several factors may contribute to this side effect:

  1. Increased Appetite: It can potentially increase appetite in some individuals, leading to increased caloric intake and weight gain.
  2. Fluid Retention: This drug may cause fluid retention or edema, which can result in temporary weight gain due to water retention.
  3. Metabolic Changes: The described medication can potentially affect metabolism or metabolic processes, although the exact mechanisms are not well-established. These metabolic changes could potentially contribute to weight gain.

Neurontin reviews

John: “Neurontin has been a game-changer for my chronic nerve pain. I suffered from excruciating pain due to a spinal injury, but since starting the therapy, my pain levels have significantly decreased. It did make me a bit drowsy at first, but that subsided over time. I’m finally able to enjoy a more active and pain-free life!”

Emily: “I was skeptical about trying Neurontin for my anxiety, but it has been a lifesaver. It has helped calm my racing thoughts and reduce anxiety levels. The initial drowsiness was a bit bothersome, but once my body adjusted, it became more manageable. I feel more in control and better able to cope with daily stressors.”

Michael: “Neurontin didn’t work well for me. I took it for neuropathic pain following surgery, but I didn’t experience significant relief. Additionally, the drowsiness and dizziness were overwhelming, affecting my daily functioning. My doctor eventually switched me to a different medication that proved more effective.”

Sarah: “Neurontin has been a godsend for my restless leg syndrome (RLS). I used to suffer from uncontrollable leg movements and sleep disruptions, but it has significantly reduced those symptoms. The initial drowsiness was challenging, but I adjusted after a few weeks. Finally getting peaceful sleep again!”

Jessica: “Neurontin has been a mixed experience for me. While it helped with my nerve pain from fibromyalgia, I did notice weight gain as a side effect. That was frustrating, but the pain relief outweighed the weight gain. It’s essential to find the right balance with lifestyle changes to manage any potential weight changes.”

David: “I’ve been taking Neurontin for my epilepsy, and it has been a game-changer. It significantly reduced my seizure frequency and allowed me to live a more normal life. The only downside was feeling drowsy in the beginning, but my body adjusted, and I haven’t experienced any major side effects since.”

Lauren: “Neurontin didn’t work well for me in managing my neuropathic pain. I tried it for several months, but unfortunately, it didn’t provide the relief I was hoping for. Additionally, the drowsiness was persistent and affected my daily activities. I’m currently exploring alternative treatment options with my doctor.”

Disclaimer: This article is about a medication used to treat erectile dysfunction. It is important to note that this medication should only be taken under the supervision of a licensed medical practitioner. The information provided here is for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Please consult with your healthcare provider before taking any medication.