What Is Viagra Super Active Plus?

viagra super active plus

Canadian Viagra Super Active Returns Joy of Intimate Life

Say goodbye to many complexes and step confidently into the new life as a real man. Canada Viagra Super Active Plus 25 mg is a next-generation product with a unique formula, enhanced by natural ingredients. Viagra Super online beneficially effects on reproductive function and treats erectile dysfunction.
The drug Generic Viagra on the properties, structure and mechanism of action is identical to Canadian Pharmacy Viagra. A key feature is that Viagra Super Active Plus 25 mg is produced by Indian pharmaceutical company. The results of the studies have shown that taking Viagra can restore normal erectile function in almost 80% of men.

Viagra 25 mg and its Impact

Just one tablet of Viagra Super Active Plus pills are able to restore confidence and ensure a strong and stable erection. This means starts to operate as soon as 15 minutes after application, and exposure duration is not more than 5 hours.
Viagra is available in 25 mg capsules and pills. The drug restores the natural reaction of a man’s body to sexual stimulation. After receiving this means Viagra 25 mg contained therein components able to activate a special enzyme (guanylate cyclase), which in turn increases the levels of cGMP (enzyme needed for an erection) in body. As a result, muscles of cavernous body relax, increasing blood flow to male genitals.
It should be noted that sildenafil, which is part of the drug has no direct relaxing effect to improve circulation. It enhances the effects of nitric oxide by controlling the activity of the enzyme PDE-5, which provides a breakdown of cGMP in cavernous body. It is noteworthy that for the beneficial effects of drug Canadian Viagra Super Active it is necessary the presence of sexual excitement.

Benefits of Generic Viagra Super Active Plus Online

Sometimes physiological causes, such as sexual abstinence, or other circulatory disorders, can cause erectile dysfunction emergence. It can be eliminated by using 25 mg of Viagra daily. This drug performs on vascular penile smooth muscle cells, and they are peculiar: veins that carried blood flow – are expanding, and those in which the blood moves – narrowed. As a result, this procedure helps ensure sustainable and stable erection. On this basis, we can
identify a number of key advantages:

  • it improves blood circulation in penis;
  • the response time is reduced to a minimum;
  • when intercourse is guaranteed a good and stable erection;
  • it stimulates release of growth hormone.

sex with viagra
Among the side effects are:

  • individual intolerance to the drug;
  • headache;
  • nausea and dizziness.

But these side effects happen to be observed on rare occasions.

In the event that there are problems with potency, you need to buy Viagra online via My Canadian Pharmacy Team – mycanadianpharmacyteam.com. Today, thanks to modern developments in pharmaceutics field every man has a chance to increase the erectile function and improve the quality of sexual intercourse.

Viagra Super Active Plus and Its Interactions with Other Medications

A single dose of antacid (magnesium hydroxide / aluminum hydroxide) simultaneously with Canadian Viagra has no effect on its bioavailability. It enhances the hypotensive effect of nitrates (concomitant use is contraindicated) and antiplatelet effect of sodium nitroprusside.

At the same time taking drug Viagra Super Active Plus with acetylsalicylic acid (150 mg) did not increase bleeding time.

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CYR3A4 inhibitors (Cimetidine, ketoconazole, itraconazole, erythromycin and others) to the concentration of sildenafil in the plasma (in particular cimetidine 800 mg – 56%, when taking sildenafil, 50 mg) reduces its excretion. In single dose of 25 mg of Viagra Super Active Plus Canada on the background of equilibrium concentration of erythromycin (receiving 500 mg twice daily for 5 days) AUC sildenafil increased by 182%, on the background of the equilibrium concentration of saquinavir (1200 mg 3 times daily) Cmax of sildenafil increased by 140% , AUC – 210%.

A single dose of 25 mg of drug Viagra online on the background of equilibrium concentration of ritonavir – a potent inhibitor of cytochrome P450 (400 mg, 2 times daily) results in 4-fold (300%) increase Cmax and 11-fold (1000%) increase AUC sildenafil.

Sildenafil has no effect on the pharmacokinetics of ritonavir and saquinavir. CYP2C9 inhibitors (tolbutamide, warfarin) of CYP2D6 (selective serotonin reuptake inhibitors, tricyclic antidepressants), thiazids and thiazide diuretics, potassium-sparing diuretics, ACE inhibitors, calcium channel blockers, beta-blockers and inducers of cytochrome P450 (rifampicin, barbiturates) do not have effect on the pharmacokinetics of sildenafil.

It is assumed that while taking drug Generic Viagra with inducers of CYP3A4 (rifampicin, etc.), its plasma concentration will decrease. AUC of the active metabolite of sildenafil is increased by 62% when receiving potassium-sparing diuretics and 102% – when receiving nonspecific beta-blockers (the clinical significance of these effects is not defined).

There were no signs of interaction with amlodipine (5 mg and 10): average additional reduction in blood pressure in the supine position is comparable to that when receiving one of sildenafil in healthy volunteers. It does not enhance hypotensive effect of alcohol in healthy volunteers with a blood alcohol concentration of up to 80 mg / dL.

Overdose of drug Viagra Symptoms

viagra and alcoholIn studies with healthy volunteers at single dose of 800 mg of sildenafil was observed increased severity of side effects.
Treatment of an overdose of a drug Viagra is symptomatic. Dialysis is ineffective because of high degree of sildenafil binding and its metabolite plasma proteins.

Precautions for Viagra Super Active Plus

Before taking Viagra it is necessary to be diagnosed with erectile dysfunction, it is obligatory to determine the potential of its causes and select appropriate treatment which should be written down in medical history. Conduct a thorough urological and general clinical examination, especially in patients with underlying cardiovascular disease, which increased sexual activity. In patients older than 65 years, with liver and severe renal insufficiency (Cl creatinine less than 30 ml / min), and while the use of inhibitors of cytochrome P450 3A4 (erythromycin, ketoconazole, itraconazole, saquinavir et al.), the initial dose is 25 mg. At the same time taking ritonavir maximum Canadian Viagra single dose should not exceed 25 mg within 48 hours.

There are post-marketing reports of rare cases, when erection lasts longer than 4 hours. It is known as priapism (read more) requiring immediate medical attention to avoid damage to penile tissue and irreversible impotence.

Safety of drug Viagra when taken with other drugs for the treatment of erectile dysfunction has not been studied, concomitant use is not recommended. Its use benefits or disadvantages is not indicated in newborns, children and women.